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Construction of linkage maps with DNA markers for human chromosomes

Nature volume 313, pages 101–105 (1985)Cite this article

Abstract

DNA markers and sampling of three-generation families can be used to construct complete linkage maps of human chromosomes. This is important in mapping disease loci and in determining the genetic or environmental component of a disease.

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Author information

Author notes

  1. David Barker

    Present address: Collaborative Research, Inc., 128 Spring Street, Lexington, Massachusetts, 02173, USA

Authors and Affiliations

  1. Howard Hughes Medical Institute and Departments of Cellular, Viral and Molecular Biology, University of Utah Medical School, Salt Lake City, Utah, 84132, USA

    Ray White, Mark Leppert, David Barker, Jon Berkowitz, Candace Brown, Patricia Callahan, Tom Holm & Leslie Jerominski

  2. Department of Medical Biophysics and Computing, University of Utah Medical School, Salt Lake City, Utah, 84132, USA

    D. Timothy Bishop

Authors
  1. Ray White
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  2. Mark Leppert
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  3. D. Timothy Bishop
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  4. David Barker
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  5. Jon Berkowitz
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  6. Candace Brown
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  7. Patricia Callahan
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  8. Tom Holm
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  9. Leslie Jerominski
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White, R., Leppert, M., Bishop, D. et al. Construction of linkage maps with DNA markers for human chromosomes. Nature 313, 101–105 (1985). https://doi.org/10.1038/313101a0

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