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Information for the dorsal–ventral pattern of the Drosophila embryo is stored as maternal mRNA

Abstract

Maternal-effect mutations in 10 loci in Drosophila produce totally ‘dorsalized’ embryos. Injection of RNA isolated from wild-type embryos into mutants at six loci partially restores dorsal–ventral polarity. For the mutant snake, injection of poly(A)+ RNA restores a complete dorsal–ventral pattern.

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Anderson, K., Nüsslein-Volhard, C. Information for the dorsal–ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature 311, 223–227 (1984). https://doi.org/10.1038/311223a0

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