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The molecular biology of immunoglobulin D

Nature volume 307, pages 417–422 (1984)Cite this article

Abstract

Immunoglobulin D (IgD) is co-expressed with immunoglobulin M (IgM) on the membranes of most B cells, yet its biological function has remained a mystery. Recent detailed information on the structure and transcription of the unusual IgD heavy chain (δ) gene in mouse suggests a complex genetic control A model is presented for the developmental regulation of IgM and IgD and roles suggested for the membrane and secreted forms of IgD in the immune network.

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Authors and Affiliations

  1. Department of Genetics, University of Wisconsin, Madison, Wisconsin, 53706, USA

    Frederick R. Blattner

  2. Department of Microbiology, University of Texas Southwestern Medical School, Dallas, Texas, 75235, USA

    Philip W. Tucker

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  1. Frederick R. Blattner
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Blattner, F., Tucker, P. The molecular biology of immunoglobulin D. Nature 307, 417–422 (1984). https://doi.org/10.1038/307417a0

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