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A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B

Nature volume 307, pages 237–241 (1984)Cite this article

Abstract

Four human complement genes, which have previously been mapped between HLA-D and HLA-B on chromosome 6, have now been aligned on a 98-kilobase (kb) section of the chromosome on the basis of four overlapping cosmid clones of genomic DNA. The C2 and factor B genes, less than 2 kb apart, are about 30 kb from two C4 genes separated from each other by about 10 kb.

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Authors and Affiliations

  1. MRC Immunochemistry Unit, Biochemistry Department, Oxford University, South Parks Road, Oxford, OX1 3QU, UK

    Michael C. Carroll, R. Duncan Campbell, David R. Bentley & Rodney R. Porter

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  1. Michael C. Carroll
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  2. R. Duncan Campbell
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  3. David R. Bentley
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  4. Rodney R. Porter
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Carroll, M., Campbell, R., Bentley, D. et al. A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B. Nature 307, 237–241 (1984). https://doi.org/10.1038/307237a0

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