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Molecular cloning of cDNA for murine interleukin-3

Nature volume 307, pages 233–237 (1984)Cite this article

Abstract

The cDNA sequence for murine interleukin-3, one of the colony stimulating factors that regulate haematopoiesis, codes for a polypeptide of 166 amino acids including a putative signal peptide. The predicted amino acid sequence indicates that formation of mature interleukin-3 involves proteolytic removal of not only the signal peptide but additional ammo-terminal amino acids.

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Authors and Affiliations

  1. Department of Biochemistry, John Curtin School of Medical Research, Australian National University, PO Box 334, Canberra, ACT, 2601, Australia

    M. C. Fung, S. Ymer, D. R. Cohen, R. M. Johnson, H. D. Campbell & I. G. Young

  2. Department of Medicine and Clinical Science, John Curtin School of Medical Research, Australian National University, PO Box 334, Canberra, ACT, 2601, Australia

    A. J. Hapel

Authors
  1. M. C. Fung
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  2. A. J. Hapel
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  3. S. Ymer
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  4. D. R. Cohen
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  5. R. M. Johnson
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  6. H. D. Campbell
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  7. I. G. Young
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Fung, M., Hapel, A., Ymer, S. et al. Molecular cloning of cDNA for murine interleukin-3. Nature 307, 233–237 (1984). https://doi.org/10.1038/307233a0

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  • DOI: https://doi.org/10.1038/307233a0

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