Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Identification and molecular cloning of the human Blym transforming gene activated in Burkitt's lymphomas

Abstract

DNAs of six Burkitt's lymphoma cell lines contained an activated transforming gene detected by transfection of NIH 3T3 cells. This gene was cloned from a recombinant library of Burkitt's lymphoma DNA and identified as a human homologue of chicken Blym-1, the transforming gene detected by transfection of chicken B-cell lymphoma DNA.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Cooper, G. M. Science 217, 801–806 (1982).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Cooper, G. M. & Neiman, P. E. Nature 287, 656–659 (1980).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Lane, M.-A., Sainten, A. & Cooper, G. M. Cell 28, 873–880 (1982).

    Article  CAS  PubMed  Google Scholar 

  4. Lane, M.-A., Neary, D. & Cooper, G. M. Nature 300, 659–661 (1982).

    Article  ADS  CAS  PubMed  Google Scholar 

  5. Goubin, G., Goldman, D. S., Luce, J., Neiman, P. E. & Cooper, G. M. Nature 302, 114–119 (1983).

    Article  ADS  CAS  PubMed  Google Scholar 

  6. Epstein, M. A. & Achong, B. G. (eds) in The Epstein–Barr Virus 321–337 (Springer, New York, 1979).

  7. Nilsson, D. K. in The Epstein–Barr Virus (eds Epstein, M. A. & Achong, B. G.) 225–281 (Springer, New York, 1979).

    Book  Google Scholar 

  8. Stashenko, P., Nadler, L. M., Hardy, R. & Schlossman, S. F. J. Immun. 125, 1678–1685 (1980).

    CAS  PubMed  Google Scholar 

  9. Benjamin, D. et al. J. Immun. 129, 1336–1342 (1982).

    CAS  PubMed  Google Scholar 

  10. Skare, J. & Strominger, J. L. Proc. natn. Acad. Sci. U.S.A. 77, 3860–3864 (1980).

    Article  ADS  CAS  Google Scholar 

  11. Powell, A. L. T., King, W. & Kieff, E. J. Virol. 29, 261–274 (1979).

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Loenen, W. A. M. & Brammar, W. J. Gene 20, 249–259 (1980).

    Article  Google Scholar 

  13. Hohn, B. & Murray, K. Proc. natn. Acad. Sci. U.S.A. 74, 3259–3269 (1977).

    Article  ADS  CAS  Google Scholar 

  14. Hanahan, D. & Meselson, M. Gene 10, 63–67 (1980).

    Article  CAS  PubMed  Google Scholar 

  15. Der, C. J., Krontiris, T. G. & Cooper, G. M. Proc. natn. Acad. Sci. U.S.A. 79, 3637–3640 (1982).

    Article  ADS  CAS  Google Scholar 

  16. Parada, L. F., Tabin, C. J., Shin, C. & Weinberg, R. A. Nature 297, 474–478 (1982).

    Article  ADS  CAS  PubMed  Google Scholar 

  17. Santos, E., Tronick, S. R., Aaronson, S. A., Pulciani, S. & Barbacid, M. Nature 298, 343–347 (1982).

    Article  ADS  CAS  PubMed  Google Scholar 

  18. Pulciani, S. et al. Nature 300, 539–542 (1982).

    Article  ADS  CAS  PubMed  Google Scholar 

  19. Der, C. J. & Cooper, G. M. Cell 32, 201–208 (1983).

    Article  CAS  PubMed  Google Scholar 

  20. Shimizu, K. et al. Proc. natn. Acad. Sci. U.S.A. 80, 2112–2116 (1983).

    Article  ADS  CAS  Google Scholar 

  21. Hall, A., Marshall, C. J., Spurr, N. K. & Weiss, R. A. Nature 303, 396–400 (1983).

    Article  ADS  CAS  PubMed  Google Scholar 

  22. Hayward, W. S., Neel, B. G. & Astrin, S. M. Nature 290, 475–480 (1981).

    Article  ADS  CAS  PubMed  Google Scholar 

  23. Cooper, G. M. & Neiman, P. E. Nature 292, 857–858 (1981).

    Article  ADS  CAS  PubMed  Google Scholar 

  24. Neiman, P. E., Payne, L. N., Jordan, L. & Weiss, R. A. Cold Spring Harb. Conf. Cell Prolif. 7, 519–528 (1980).

    CAS  Google Scholar 

  25. Klein, G. Nature 294, 313–318 (1981).

    Article  ADS  CAS  PubMed  Google Scholar 

  26. Rowley, J. Science 216, 749–751 (1982).

    Article  ADS  CAS  PubMed  Google Scholar 

  27. Dalla-Favera, R. et al. Proc. natn. Acad. Sci. U.S.A. 79, 7824–7827 (1982).

    Article  ADS  CAS  Google Scholar 

  28. Taub, R. et al. Proc. natn. Acad. Sci. U.S.A. 79, 7837–7841 (1982).

    Article  ADS  CAS  Google Scholar 

  29. Neel, B. G., Jhanwar, S. C., Chaganti, R. S. K. & Hayward, W. S. Proc. natn. Acad. Sci. U.S.A. 79, 7842–7846 (1982).

    Article  ADS  CAS  Google Scholar 

  30. Marcu, K. B. et al. Proc. natn. Acad. Sci. U.S.A. 80, 519–523 (1983).

    Article  ADS  CAS  Google Scholar 

  31. Lane, M.-A., Sainten, A. & Cooper, G. M. Proc. natn. Acad. Sci. U.S.A. 78, 5185–5189 (1981).

    Article  ADS  CAS  Google Scholar 

  32. Nusse, R. & Varmus, H. E. Cell 31, 99–109 (1982).

    Article  CAS  PubMed  Google Scholar 

  33. Adams, J. M. et al. Proc. natn. Acad. Sci. U.S.A. 79, 6966–6970 (1982).

    Article  ADS  CAS  Google Scholar 

  34. Calame, K. et al. Proc. natn. Acad. Sci. U.S.A. 79, 6994–6998 (1982).

    Article  ADS  CAS  Google Scholar 

  35. Shen-Ong, G. L. C., Keath, E. J., Piccoli, S. P. & Cole, M. D. Cell 31, 443–452 (1982).

    Article  CAS  PubMed  Google Scholar 

  36. Crews, S., Barth, R., Hood, L., Prehn, J. & Calame, K. Science 218, 1319–1321 (1982).

    Article  ADS  CAS  PubMed  Google Scholar 

  37. Shen-Ong, G. L. C., Keath, E. J., Piccoli, S. P. & Cole, M. D. Cell 31, 443–452 (1982).

    Article  CAS  PubMed  Google Scholar 

  38. Crews, S., Barth, R., Hood, L., Prehn, J. & Calame, K. Science 218, 1319–1321 (1982).

    Article  ADS  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Diamond, A., Cooper, G., Ritz, J. et al. Identification and molecular cloning of the human Blym transforming gene activated in Burkitt's lymphomas. Nature 305, 112–116 (1983). https://doi.org/10.1038/305112a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/305112a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing