The discovery that the oncogenes of retroviruses are derived from cellular genes has led to a search for differences between the viral gene and its cellular counterpart that might explain the oncogenic activity of the former. Two oncogenes, the abl and the src genes, have recently come under such scrutiny. The src gene will be the subject of a later article: here, Jean Yin Jen Wang discusses the abl gene.
Article PDF
References
Wang, J.Y.J. & Baltimore, D. Molec. cell. Biol. (in the press).
Wang, J.Y.J. et al. (in preparation).
Wang, J.Y.J., Queen, C. & Baltimore, D. J. biol. Chem. 257, 13181 (1982).
Wang, J.Y.J. & Baltimore, D. (in preparation).
Lee, R. et al. (in preparation).
Kitamura, N. et al. Nature 297, 205 (1982).
Shibuya, M. & Hanafusa, H. Cell 30, 787 (1982).
Hempe, A. et al. Cell 30, 775 (1982).
Prywes, R., Foulkes, J.G., Rosenberg, N. & Baltimore, D. (submitted).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wang, J. Evolution of oncogenes: From c-abl to v-abl. Nature 304, 400 (1983). https://doi.org/10.1038/304400a0
Issue Date:
DOI: https://doi.org/10.1038/304400a0