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Molecular characterization of two myosin heavy chain genes expressed in the adult heart

Nature volume 297, pages 659–664 (1982)Cite this article

Abstract

Four cDNA clones containing cardiac myosin heavy chain (MHC) inserts have been characterized. Hybridization and nucleotide sequence analysis identify two different MHC genes coding for proteins of different length that are both specifically expressed in the adult heart. The nucleotide and amino acid sequences reveal a highly conserved structure in the light meromyosin portion of MHC from striated muscle tissues.

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Author notes

  1. V. Mahdavi, M. Periasamy & B. Nadal-Ginard

    Present address: Department of Pediatrics, Harvard Medical School, Department of Cardiology, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts, 02115, USA

Authors and Affiliations

  1. Albert Einstein College of Medicine, New York, New York, 10461, USA

    V. Mahdavi, M. Periasamy & B. Nadal-Ginard

Authors
  1. V. Mahdavi
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  2. M. Periasamy
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  3. B. Nadal-Ginard
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Mahdavi, V., Periasamy, M. & Nadal-Ginard, B. Molecular characterization of two myosin heavy chain genes expressed in the adult heart. Nature 297, 659–664 (1982). https://doi.org/10.1038/297659a0

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