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Unusual physical organization of the Halobacterium genome

Nature volume 295, pages 384–389 (1982)Cite this article

Abstract

The genomes of the extremely halophilic bacteria, Halobacterium halobium and Halobacterium volcanii, contain many repeated sequences. These sequences comprise many families, seem to be highly mobile and are arranged in both clustered and dispersed fashions within these genomes. At least some repeated sequences are more strongly conserved between the two species than are unique sequence DNAs.

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References

  1. Woese, C. R. Scient. Am. 244(6), 94–106 (1981).

    Article  ADS  Google Scholar 

  2. Fox, G. E. et al. Science 209, 457–463 (1980).

    Article  ADS  CAS  Google Scholar 

  3. Doolittle, W. F. Trends biochem. Sci. 5, 146–149 (1980).

    Article  CAS  Google Scholar 

  4. Bayley, S. T. & Mortem, R. A. CRC crit. Rev. Microbiol. 6, 151–205 (1978).

    Article  CAS  Google Scholar 

  5. Mitchell, R. M., Loeblich, L. A., Klotz, L. C. & Loeblich, A. R. III Science 204, 1082–1084 (1979).

    Article  ADS  CAS  Google Scholar 

  6. Searcy, D. G. & Doyle, E. K. Int. J. Syst. Bact. 25, 286–289 (1975).

    Article  CAS  Google Scholar 

  7. Moore, R. L. & McCarthy, B. J. J. Bact. 99, 248–254 (1969).

    CAS  PubMed  Google Scholar 

  8. Moore, R. L. & McCarthy, B. J. J. Bact. 99, 255–262 (1969).

    CAS  PubMed  Google Scholar 

  9. Weidinger, G., Klotz, G. & Goebel, W. Plasmid 2, 377–386 (1979).

    Article  CAS  Google Scholar 

  10. Pfeifer, F., Weidinger, G. & Goebel, W. J. Bact. 145, 375–381 (1981).

    CAS  PubMed  Google Scholar 

  11. Rigby, P. W. J., Dieckmann, M., Rhodes, C. & Berg, P. J. molec. Biol. 113, 237–251 (1977).

    Article  CAS  Google Scholar 

  12. Southern, E. M. J. molec. Biol. 98, 503–517 (1975).

    Article  CAS  Google Scholar 

  13. Bedbrook, J., Jones, J. & Flavell, R. Cold Spring Harb. Symp. quant. Biol. 45, 755–760 (1981).

    Article  CAS  Google Scholar 

  14. Scheller, R. H. et al. J. molec. Biol. 149, 15–39 (1981).

    Article  CAS  Google Scholar 

  15. Graf, H. Biochim. biophys. Acta 564, 225–234 (1979).

    Article  CAS  Google Scholar 

  16. Norgard, M. V., Keem, K. & Monahan, J. J. Gene 3, 279–292 (1978).

    Article  CAS  Google Scholar 

  17. Birnboim, H. C. & Doly, J. Nucleic Acids Res. 7, 1513–1523 (1979).

    Article  CAS  Google Scholar 

  18. Hofman, J. D., Lau, R. H. & Doolittle, W. F. Nucleic Acids Res. 7, 1331–1334 (1979).

    Article  Google Scholar 

  19. Jeffreys, A. J. & Flavell, R. A. Cell 12, 429–439 (1977).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Biochemistry, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada, B3H 4H7

    Carmen Sapienza & W. Ford Doolittle

Authors
  1. Carmen Sapienza
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  2. W. Ford Doolittle
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Sapienza, C., Doolittle, W. Unusual physical organization of the Halobacterium genome. Nature 295, 384–389 (1982). https://doi.org/10.1038/295384a0

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