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Molecular cloning and characterization of cDNA sequences coding for rat relaxin

Nature volume 291, pages 127–131 (1981)Cite this article

Abstract

Using a synthetic oligonucleotide primer, cloned DNA fragments, each containing the entire coding sequence of rat relaxin, have been isolated from a clone ‘bank’ of ovarian mRNA sequences. The nucleotide sequence of these clones demonstrates that relaxin is synthesized as a preprorelaxin molecule with an unexpectedly large connecting peptide of 105 amino acid residues.

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Authors and Affiliations

  1. Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia, 3052

    P. Hudson, J. Haley & H. Niall

  2. Department of Genetics, Research School of Biological Sciences, Australian National University, Canberra, Australia, 2601

    M. Cronk & J. Shine

Authors
  1. P. Hudson
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  2. J. Haley
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  3. M. Cronk
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  4. J. Shine
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  5. H. Niall
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Hudson, P., Haley, J., Cronk, M. et al. Molecular cloning and characterization of cDNA sequences coding for rat relaxin. Nature 291, 127–131 (1981). https://doi.org/10.1038/291127a0

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