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Primary structure of a murine transplantation antigen

Nature volume 291, pages 35–39 (1981)Cite this article

Abstract

A radiochemical technique has been used to determine the primary structure of a murine H-2Kb molecule, a 346-residue glycoprotein subunit attached to a 99-residue β2-microglobulin subunit. Comparison of this structure with those available for other murine H–2 antigens and human HLA molecules suggests an evolutionary origin of MHC products.

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Authors and Affiliations

  1. Laboratory of Immunogenetics, Building 8, Room 100, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20205, USA

    J. E. Coligan & T. J. Kindt

  2. Departments of Microbiology and Immunology and Cell Biology, Albert Einstein College of Medicine, Bronx, New York, 10461, USA

    H. Uehara, J. Martinko & S. G. Nathenson

Authors
  1. J. E. Coligan
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  2. T. J. Kindt
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  3. H. Uehara
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  4. J. Martinko
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  5. S. G. Nathenson
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Coligan, J., Kindt, T., Uehara, H. et al. Primary structure of a murine transplantation antigen. Nature 291, 35–39 (1981). https://doi.org/10.1038/291035a0

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