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Mouse liver and salivary gland α-amylase mRNAs differ only in 5′ non-translated sequences

Abstract

The sequence of the 1,773-nucleotide major and 1,806-nucleotide minor mouse liver α-amylase mRNAs differ only with respect to approximately 30 additional residues at the extreme 5′ terminus of the minor species. Comparison of the liver α-amylase mRNAs with their salivary gland counterpart reveals that these mRNAs share identical coding and 3′-noncoding sequences, but contain distinct 5′-terminal residues. These data suggest that all three mRNAs might be transcribed from the same gene.

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Hagenbüchle, O., Tosi, M., Schibler, U. et al. Mouse liver and salivary gland α-amylase mRNAs differ only in 5′ non-translated sequences. Nature 289, 643–646 (1981). https://doi.org/10.1038/289643a0

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