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Human leukocyte and fibroblast interferons are structurally related

Abstract

The coding sequences of the cDNAs of cloned human leukocyte interferon I and human fibroblast interferon show homologies of 45% at the nucleotide and 29% at the amino acid level. We conclude that the two genes were derived from a common ancestor.

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Taniguchi, T., Mantei, N., Schwarzstein, M. et al. Human leukocyte and fibroblast interferons are structurally related. Nature 285, 547–549 (1980). https://doi.org/10.1038/285547a0

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