Abstract
The complete chromosomal mouse βmaj-globin gene, including its intervening and flanking sequences, has been cloned in the monkey virus SV40. The mouse gene is transcribed, processed and translated in infected monkey kidney cells to yield mouse βmaj-globin.
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References
Tilghman, S. M. et al. Proc. natn. Acad. Sci. U.S.A. 74, 4406–4410 (1977).
Tilghman, S. et al. Proc. natn. Acad. Sci. U.S.A. 75, 725–729 (1978).
Tiemeier, D. C. et al. Cell 14, 237–245 (1978).
Leder, A. et al. Proc. natn. Acad. Sci. U.S.A. 75, 6187–6191 (1978).
Konkel, D. A., Tilghman, S. M. & Leder, P. Cell 15, 1125–1132 (1978).
Hamer, D. H., Davoli, D., Thomas, C. A. Jr & Fareed, G. C. J. molec. Biol. 112, 155–182 (1977).
Hamer, D. H. in Recombinant Molecules: Impact on Science and Society (eds Beers, R. F. & Bassett, E. G.) 317–336 (Raven, New York, 1977).
Hamer, D. H. in Genetic Manipulation as it Affects the Cancer Problem, 37–47 (Academic, New York, 1977).
Upcroft, P. et al. Proc. natn. Acad. Sci. U.S.A. 75, 2117–2121 (1978).
Hamer, D. H., Smith, K. D., Boyer, S. H. & Leder, P. Cell 17, 725–736 (1979).
Mulligan, R., Howard, B. & Berg, P. Nature 277, 108–114 (1979).
Hamer, D. H. & Leder, P. Cell 17, 737–747 (1979).
Scherrer, K. in Fundamental Techniques in Virology (eds Habel, K. & Salzman, N. P.) 413–432 (Academic, New York, 1969).
Aviv, H. & Leder, P. Proc. natn. Acad. Sci. U.S.A. 69, 1408–1412 (1972).
McMaster, G. K. & Carmichael, G. G. Proc. natn. Acad. Sci. U.S.A. 74, 4835–4838 (1977).
Alwine, J. C., Kemp, D. J. & Stark, G. R. Proc. natn. Acad. Sci. U.S.A. 74, 5350–5354 (1977).
Ghosh, P. et al. J. biol. Chem. 253, 3643–3647 (1978).
Lai, C. J., Dhar, R. & Khoury, G. Cell 14, 971–982 (1978).
Maizel, J. V. Jr in Methods in Virology Vol. 5, 179–246 (Academic, New York, 1971).
O'Farrell, P. Z., Goodman, H. M. & O'Farrell, P. H. Cell 12, 1133–1142 (1977).
Elder, J. H., Pickett, R. A., Hampton, J. & Lerner, R. A. J biol. Chem. 252, 6510–6515 (1977).
Baglioni, C. Biochim. biophys. Acta 59, 437–440 (1962).
Gilman, J. G. Science 178, 868–874 (1972).
Wigler, M., Pellicer, A., Silverstein, S. & Axel, R. Cell 14, 725–731 (1978).
Weissmann, C. et al. 11th Miami Winter Symp. 1979 (in the press).
Bolivar, F. et al. Gene 2, 95–113 (1977).
Fiers, W. et al. Nature 273, 113–120 (1978).
Reddy, V. B. et al. Science 200, 494–502 (1978).
Hirt, B. J. molec. Biol. 26, 365–369 (1967).
Deisseroth, A., Barker, J., Anderson, W. F. & Nienhuis, A. Proc. natn. Acad. Sci. U.S.A. 72, 2682–2686 (1975).
Clegg, J. B., Naughton, M. A. & Weatherall, D. F. J. molec. Biol. 19, 91–108 (1966).
Kessler, S. W. J. Immun. 115, 1617–1624 (1975).
Bonner, W. M. & Laskeyt, R. A. Eur. J. Biochem. 46, 83–88 (1974).
Goff, S. P. & Berg, P. Cell 9, 695–705 (1976).
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Hamer, D., Leder, P. Expression of the chromosomal mouse βmaj-globin gene cloned in SV40. Nature 281, 35–40 (1979). https://doi.org/10.1038/281035a0
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DOI: https://doi.org/10.1038/281035a0
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