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Embryonic development of identified neurones: differentiation from neuroblast to neurone

Nature volume 280, pages 208–214 (1979)Cite this article

Abstract

Individually identified neurones are sufficiently large and accessible in grasshopper embryos to permit visualisation and impalement with intracellular microelectrodes from the time of their birth to their maturation. In this article part of the temporal pattern of differentiation from an identified neuroblast (precursor cell) to a group of identified neurones is described.

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References

  1. Kuffler, S. W. & Nicholls, J. G. From Neuron to Brain (Sinauer, Boston, 1976).

    Google Scholar 

  2. Kandel, E. R. Cellular Basis of Behavior (Freeman, San Francisco, 1976).

    Google Scholar 

  3. Hoyle, G. (ed.) Identified Neurons and Behavior of Arthropods (Plenum, New York, 1977).

    Google Scholar 

  4. Faber, D. S. & Korn, H. (eds) Neurobiology of the Mauthner Cell (Raven, New York, 1978).

  5. Plotnikova, S. I. J. evolut. biochem. Physiol. 5, 339–341 (1969).

    Google Scholar 

  6. Crossman, A. R., Kerkut, G. A., Pitman, R. M. & Walker, R. J. comp. Biochem. Physiol. 40A, 579–596 (1971).

    Article  Google Scholar 

  7. Hoyle, G., Dagan, D., Moberly, B. & Colquhoun, W. J. exp. Zool. 187, 159–165 (1974).

    Article  Google Scholar 

  8. O'Shea, M. & Evans, P. Soc. Neurosci. 3, 187 (1977).

    Google Scholar 

  9. Evans, P. & O'Shea, M. Nature 270, 275–279 (1977); J. exp. Biol. 73, 235–260 (1978).

    Article  Google Scholar 

  10. Heitler, W. J. & Goodman, C. S. J. exp. Biol. 76, 63–84 (1978).

    Google Scholar 

  11. Goodman, C. S. & Heitler, W. J. Soc. Neurosci. 3, 426 (1977); J. exp. Biol. (in the press).

    Google Scholar 

  12. Sulston, J. E. Phil. Trans. R. Soc. B 275, 287–297 (1976).

    Article  CAS  Google Scholar 

  13. Sulston, J. E. & Horvitz, H. R. Devl Biol. 56, 110–156 (1977).

    Article  CAS  Google Scholar 

  14. Goodman, C. S. & Spitzer, N. C. Soc. Neurosci. 4, 113 (1978).

    Google Scholar 

  15. Spitzer, N. C. & Goodman, C. S. Soc. Neurosci. 4, 127 (1978).

    Google Scholar 

  16. Wheeler, W. M. J. Morph. 4, 337–343 (1891); 8, 1–160 (1893).

    Article  Google Scholar 

  17. Baden, V. J. Morph. 60, 159–190 (1936).

    Article  Google Scholar 

  18. Roonwal, M. L. Phil. Trans. R. Soc. B227, 175–244 (1937).

    Article  Google Scholar 

  19. Anderson, D. T. in Developmental Systems: Insects (eds Counce, S. J. & Waddington, C. H.) (Academic, New York, 1972).

    Google Scholar 

  20. Bate, C. M. J. Embryol. exp. Morph. 35, 107–123 (1976).

    CAS  PubMed  Google Scholar 

  21. Stuart, A. E., Hudspeth, A. J. & Hall, Z. W. Cell Tissue Res. 153, 55–61 (1974).

    Article  CAS  Google Scholar 

  22. Wallace, B. G., Talamo, B. R., Evans, P. D. & Kravitz, E. A. Brain Res. 74, 349–355 (1974).

    Article  CAS  Google Scholar 

  23. Evans, P. D., Kravitz, E. A., Talamo, B. R. & Wallace, B. G. J. Physiol., Lond. 262, 51–70 (1976).

    Article  CAS  Google Scholar 

  24. Goodman, C. S., O'Shea, M., McCaman, R. E. & Spitzer, N. C. Science 204, 1219–1222 (1979).

    Article  ADS  CAS  Google Scholar 

  25. Stewart, W. W. Cell 14, 741–759 (1978).

    Article  CAS  Google Scholar 

  26. Narahashi, T. Physiol. Rev. 54, 813–889 (1974).

    Article  CAS  Google Scholar 

  27. Lopresti, V., Macagno, E. R. & Levinthal, C. Proc. natn. Acad. Sci. U.S.A. 70, 433–473 (1974).

    Article  ADS  Google Scholar 

  28. Schacher, S. & Kandel, E. R. Soc. Neurosci. 4, 126 (1978).

    Google Scholar 

  29. Spitzer, N. C. & Baccaglini, P. I. Brain Res. 107, 610–616 (1976).

    Article  CAS  Google Scholar 

  30. Baccaglini, P. I. & Spitzer, N. C. J. Physiol., Lond. 271, 93–117 (1977).

    Article  CAS  Google Scholar 

  31. Baccaglini, P. I. J. Physiol., Lond. 283, 585–604 (1978).

    Article  CAS  Google Scholar 

  32. Spitzer, N. C. & Lamborghini, J. E. Proc. natn. Acad. Sci. U.S.A. 73, 1641–1645 (1976).

    Article  ADS  CAS  Google Scholar 

  33. Willard, A. L. Soc. Neurosci. 3, 123 (1977); and in preparation.

    Google Scholar 

  34. Potter, D. D., Furshpan, E. J. & Lennox, E. S. Proc. natn. Acad. Sci. U.S.A. 55, 328–336 (1966).

    Article  ADS  CAS  Google Scholar 

  35. Warner, A. E. in Simple Nervous Systems (eds Newth, D. R. & Usherwood, P. N. R.) (Arnold, London, 1975).

    Google Scholar 

  36. Blackshaw, S. E. & Warner, A. E. J. Physiol., Lond. 255, 209–230 (1976).

    Article  CAS  Google Scholar 

  37. Spitzer, N. C. & Spitzer, J. L. Am. Zool. 15, 781 (1975).

    Google Scholar 

  38. Spitzer, N. C. Soc. Neurosci. 2, 204 (1976).

    Google Scholar 

  39. Cochard, P., Goldstein, M. & Black, I. B. Soc. Neurosci. 4, 109 (1978); Proc. natn. Acad. Sci. U.S.A. 75, 2986–2990. (1978).

    Google Scholar 

  40. Rothman, T. P., Gershon, M. D. & Holtzer, H. Devl Biol. 65, 322–341 (1978).

    Article  CAS  Google Scholar 

  41. Chiappinelli, V., Giacobini, E., Pilar, G. & Uchimura, H.K. Physiol., Lond. 257, 749–766 (1976).

    Article  CAS  Google Scholar 

  42. Sanes, J. R. & Hildebrand, J. G. Devl Biol. 52, 105–120 (1976).

    Article  CAS  Google Scholar 

  43. LeDouarin, N. M., Renaud, D., Teillet, M. A. & LeDouarin, G. H. Proc. natn. Acad. Sci. U.S.A. 72, 728–732 (1975).

    Article  ADS  CAS  Google Scholar 

  44. LeDouarin, N. M., Teillet, M. A., Ziller, C. & Smith, J. Proc. natn. Acad. Sci. U.S.A. 75, 2030–2034 (1978).

    Article  ADS  CAS  Google Scholar 

  45. Bentley, D., Keshishian, H., Shankland, M. & Raymond, A. J. Embryol. exp. Morph. (in the press).

Download references

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Author notes

  1. Corey S. Goodman

    Present address: Department of Biological Sciences, Stanford University, Stanford, California, 94305

Authors and Affiliations

  1. Department of Biology B-022, University of California at San Diego, La Jolla, California, 92093

    Corey S. Goodman & Nicholas C. Spitzer

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  1. Corey S. Goodman
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  2. Nicholas C. Spitzer
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Goodman, C., Spitzer, N. Embryonic development of identified neurones: differentiation from neuroblast to neurone. Nature 280, 208–214 (1979). https://doi.org/10.1038/280208a0

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