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Prediction of protein structure from amino acid sequence

Nature volume 271, pages 15–20 (1978)Cite this article

Abstract

In principle, it is possible to predict theoretically the three-dimensional structure of a protein from its amino acid sequence. Recently substantial progress towards this goal has been made by the use of simple models to represent protein conformation and interatomic interactions, together with the knowledge gained from analyses of known protein structures.

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Authors and Affiliations

  1. Laboratory of Molecular Biophysics, Department of Zoology, South Parks Road, Oxford, UK

    Michael J. E. Sternberg & Janet M. Thornton

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  1. Michael J. E. Sternberg
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  2. Janet M. Thornton
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Sternberg, M., Thornton, J. Prediction of protein structure from amino acid sequence. Nature 271, 15–20 (1978). https://doi.org/10.1038/271015a0

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