Abstract
SMOOTH muscle antibody (SMA) found in the sera of some patients with active chronic hepatitis (ACH)1 has been shown to contain specific anti-actin antibody2,3. These SMA sera have been used to demonstrate the presence of the corresponding antigen in normal2 and neoplastic4–6 ‘non-muscle’ tissues. We have demonstrated that SMA serum reacts with normal, neoplastic and foetal astrocytes but not with neurone cell bodies5,7. The present report deals with the reaction of SMA with synaptic endings in the central nervous system (CNS).
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TOH, B., GALLICHIO, H., JEFFREY, P. et al. Anti-actin stains synapses. Nature 264, 648–650 (1976). https://doi.org/10.1038/264648a0
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DOI: https://doi.org/10.1038/264648a0
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