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Induction of specific proteins in hyphae of Achlya ambisexualis by the steroid hormone antheridiol

Abstract

SEXUAL differentiation in the male and female strains of the water mould Achlya ambisexualis occurs through a series of stages mediated by steroid hormones1. The species-specific and sex-specific hormones, antheridiol and oogoniol2, initiate the development of the male and female sex organs, respectively. Because antheridiol induction depends on RNA and protein synthesis3 and steroid hormones are thought to influence the synthesis of specific proteins in the target cells4, we have investigated the pattern of proteins synthesised in the male strain of A. ambisexualis after administration of antheridiol. We found an ‘induced protein’ with a molecular weight of 69,000. It was detectable 1 h after addition of the hormone. This is analogous to the effect of oestradiol on protein synthesis in the uterus of immature rats5,6.

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GRONER, B., HYNES, N., SIPPEL, A. et al. Induction of specific proteins in hyphae of Achlya ambisexualis by the steroid hormone antheridiol. Nature 261, 599–601 (1976). https://doi.org/10.1038/261599a0

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