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Reiteration frequency of the gene for tissue-specific histone H5 in the chicken genome

Nature volume 259, pages 635–638 (1976)Cite this article

Abstract

Chicken erythroid cells contain a tissue specific histone known as H5 in addition to the five major histone species found in other organisms. The mRNA coding for this histone has been isolated by indirect immuno-precipitation from immature, non-dividing reticulocytes in which this is the only histone synthesised. The mRNA has been modified by the enzymatic addition of a 3′ polyadenylic acid tract, and transcribed into complementary DNA (cDNA) using the RNA-dependent DNA-polymerase from avian myeloblastosis virus. Studies on the hybridisation of this cDNA indicate that the gene coding for the H5 histone is reiterated 10 times in the chicken genome.

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  1. Department of Biochemistry, University of Adelaide, Adelaide, South Australia, 5001

    A. C. Scott & J. R. E. Wells

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  1. A. C. Scott
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  2. J. R. E. Wells
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Scott, A., Wells, J. Reiteration frequency of the gene for tissue-specific histone H5 in the chicken genome. Nature 259, 635–638 (1976). https://doi.org/10.1038/259635a0

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