Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Induction of photoreceptor voltage noise in the dark in Drosophila mutant

Abstract

RANDOMLY occurring, discrete voltage fluctuations (quantum bumps) have been recorded in photoreceptors of several arthropods1–4. It is thought that these bumps sum to produce the receptor potential5,6. We have investigated the relationship between photoexcitation of the visual pigment and the production of quantum bumps using a mutant of Drosophila melanogaster—a third chromosome recessive mutant described by Cosens and Manning7, in which the electroretinogram decays to baseline during a strong, prolonged stimulus. We will call this mutant the transient receptor potential mutant (trp).

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Yeandle, S., thesis, Johns Hopkins University (1957).

  2. Kirschfeld, K., in The Functional Organization of the Compound Eye, 291–307 (edit. by Bernhard, C. G.) (Pergamon, Oxford, 1966).

    Google Scholar 

  3. Sholes, J., Cold Spring Harb. Symp. quant. Biol., 30, 517–527 (1965).

    Article  Google Scholar 

  4. Fourtes, M. G. F., and Yeandle, S., J. gen. Physiol., 47, 443–463 (1964).

    Article  Google Scholar 

  5. Dodge, F. A., Knight, B. W., and Toyoda, J., Science, 160, 88–90 (1968).

    Article  ADS  Google Scholar 

  6. Wu, C-F., and Pak, W. L., J. gen. Physiol., 66, 149–168 (1975).

    Article  CAS  Google Scholar 

  7. Cosens, D., and Manning, A., Nature, 224, 285–287 (1969).

    Article  ADS  CAS  Google Scholar 

  8. Minke, B., Wu, C-F., and Pak, W. L., J. comp. Physiol., 98, 345–355 (1975).

    Article  Google Scholar 

  9. Cosens, D., and Briscoe, D., J. Insect Physiol., 18, 627–632 (1972).

    Article  Google Scholar 

  10. Nolte, J., and Brown, J. E., J. gen. Physiol., 59, 186–200 (1972).

    Article  CAS  Google Scholar 

  11. Hillman, P., Hochstein, S., and Minke, B., Science, 175, 1486–1488 (1972).

    Article  ADS  CAS  Google Scholar 

  12. Hochstein, S., Minke, B., and Hillman, P., J. gen. Physiol., 62, 105–128 (1973).

    Article  CAS  Google Scholar 

  13. Minke, B., Hochstein, S., and Hillman, P., J. gen. Physiol., 62, 787–791 (1973).

    Article  CAS  Google Scholar 

  14. Muijser, H., Leutscher-Hazelhoff, J. T., Stavenga, D. G., and Kuiper, J. E., Nature, 254, 520–522 (1975).

    Article  ADS  CAS  Google Scholar 

  15. Pak, W. L., and Lidington, K. J., J. gen. Physiol., 63, 740–756 (1974).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MINKE, B., WU, CF. & PAK, W. Induction of photoreceptor voltage noise in the dark in Drosophila mutant. Nature 258, 84–87 (1975). https://doi.org/10.1038/258084a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/258084a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing