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Serological identification of HL-A-linked human ‘Ia-type’ antigens

Abstract

THE Ir genetic region of the mouse which lies between the H-2K and H-2D loci that control the original serologically detectable H-2 specificities, has also been shown to contain genes controlling a new set of serological specificities called Ia for immune associated. Antisera raised by cross immunisation between H-2 recombinant strains have been shown to recognise the products of several genes within the Ir region (reviewed in ref. 1). Unlike the H-2K and H-2D antigens the Ia antigens have a tissue distribution that often does not include T lymphocytes.

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JONES, E., GOODFELLOW, P., BODMER, J. et al. Serological identification of HL-A-linked human ‘Ia-type’ antigens. Nature 256, 650–652 (1975). https://doi.org/10.1038/256650a0

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