Abstract
SINCE Steele attributed hyperglycaemic activity to the corpus cardiacum of the cockroach neurosecretory system1–3, it has been demonstrated in other species of Orthoptera4–10 and in Diptera11,12 and Hymenoptera13. Although extracts of corpora cardiaca from the blowflies Phormia11 and Calliphora14 and the silk moth Cecropia15 seem to be inactive, the hyperglycaemic hormone is liberated from the Calliphora gland by electrical12 or mechanical14 stimulation in situ. Similarly, extracts from Locusta6,16 and Phormia11 are poorly active intraspecifically, but are hyperglycaemic when injected into the cockroach. The nutritional state of the recipient is apparently crucial in determining the extent of the response11.
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References
Steele, J. E., Nature, 192, 680–681 (1961).
Steele, J. E., Gen. comp. Endocr., 3, 46–52 (1963).
Goldsworthy, G. J., and Mordue, W., J. Endocr., 60, 529–558 (1974).
Bowers, W. S., and Friedman, S., Nature, 198, 685 (1963).
Wiens, A. W., and Gilbert, L. I., J. Insect Physiol., 13, 779–794 (1967).
Goldsworthy, G. J., J. Insect Physiol., 15, 2131–2140 (1969).
Keeley, L. L., and Friedman, S., Gen. comp. Endocr., 8, 129–134 (1967).
Brown, B. E., Gen. comp. Endocr., 5, 387–401 (1965).
Dutrieu, J., and Gourdoux, L., C. r. hebd. Séanc. Acad. Sci., 265, 1067–1070 (1967).
Natalizi, G. M., Pansa, M. C., D'Ajello, V., Casaglia, O., Bettini, S., and Frontali, N., J. Insect Physiol., 16, 1827–1836 (1970).
Friedman, S., J. Insect Physiol., 13, 397–405 (1967).
Normann, T. C., and Duve, H., Gen. comp. Endocr., 12, 449–459 (1969).
Natalizi, G. M., and Frontali, N., J. Insect Physiol., 12, 1279–1287 (1966).
Vejbjerg, K., and Norman, T. C., J. Insect Physiol., 20, 1189–1192 (1974).
Wiens, A. W., and Gilbert, L. I., Comp. Biochem. Physiol., 21, 145–159 (1967).
Mordue, W., and Goldsworthy, G. J., Gen. comp. Endocr., 12, 360–369 (1969).
Goldsworthy, G. J., J. Insect Physiol., 15, 2131–2140 (1969).
Goldsworthy, G. J., Gen. comp. Endocr., 14, 78–85 (1970).
Bromer, W. W., Sinn, L. G., and Behrens, O. K., J. Am. chem. Soc., 79, 2807–2810 (1957).
Thomsen, J., Kristiansen, K., Brunfeldt, K., and Sundby, F., FEBS Lett., 21, 315–319 (1972).
Bromer, W. W., Boncher, M. E., and Koffenberger, J. E., Jr., J. biol. Chem., 246, 2822–2827 (1971).
Dayhoff, M. O. (ed.), in Atlas of protein sequence and structure, 5, D–8 (National Biomedical Research Foundation, Silver Spring, Maryland, 1972).
Sundby, F., Frandsen, E. K., Thomsen, J., Kristiansen, K., and Brunfeldt, K., FEBS Lett., 26, 289–293 (1972).
McLaughlin, P. J., and Dayhoff, M. O., in Atlas of protein sequence and structure, 5 (edit. by Dayhoff, M. O.), 50 (National Biomedical Research Foundation, Silver Spring, Maryland, 1972).
Tager, H. S., and Steiner, D. F., Proc. natn. Acad. Sci. U.S.A., 70, 2321–2325 (1973).
Ralph, C. L., and McCarthy, R., Nature, 203, 1195–1196 (1964).
Highnam, K. C., and Goldsworthy, G. J., Gen. comp. Endocr., 18, 83–88 (1972).
Ornstein, L., and Davis, J. B., Disc electrophoresis (Distillation Products Industries, Rochester, New York, 1962).
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TAGER, H., MARKESE, J., SPIERS, R. et al. Glucagon-like immunoreactivity in insect corpus cardiacum. Nature 254, 707–708 (1975). https://doi.org/10.1038/254707a0
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DOI: https://doi.org/10.1038/254707a0
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