Abstract
CONGENITALLY athymic (nude) mice have been used for the heterotransplantation and maintenance of human tumours1–6. In many cases aplasia of the thymus is sufficient to allow tumour growth and other immunosuppressive treatments are apparently unnecessary. Here we describe how infected cells taken from a fatal case of East Coast fever (ECF), regularly produced tumour-like masses only in irradiated athymic mice.
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IRVIN, A., STAGG, D., KANHAI, G. et al. Heterotransplantation of Theileria parva-infected cells to athymic mice. Nature 253, 549–550 (1975). https://doi.org/10.1038/253549a0
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DOI: https://doi.org/10.1038/253549a0
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