Abstract
THERE is abundant experimental evidence that certain chromium compounds are carcinogenic in animals1,2. There are also epidemiological data which suggest that chromium compounds are carcinogenic in man2,4. Calcium chromate especially, produces epithelial lung tumours both by intrabronchial implantation1 and sarcomata by intramuscular administration to rats3. In epidemiological studies Bidstrup and Case4 reported a significantly high lung cancer mortality in men who worked in chromate-producing factories, and concluded that the most likely explanation of this increased risk was due to an occupational carcinogen.
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VENITT, S., LEVY, L. Mutagenicity of chromates in bacteria and its relevance to chromate carcinogenesis. Nature 250, 493–495 (1974). https://doi.org/10.1038/250493a0
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DOI: https://doi.org/10.1038/250493a0
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