Abstract
GLYCOPROTEINS and other complex carbohydrates on the cell surfaces have been thought to be involved in many biological interactions1. Most enveloped viruses contain at least one glycoprotein component1. In avian sarcoma and leukaemia viruses some of the glycoproteins are located on the surfaces of the particles as projections composed of spikes and knobs2–4. Although their role is not well understood, the glycoproteins are believed to be involved in the determination of host range specificity, induction of neutralising antibody and interference capacity2,5–11. Rous sarcoma virus contains several glycoproteins10–13, and infectious and non-infectious strains of Rous sarcoma virus differ in major glycoprotein components14,15. We report here the results of purification of the major glycoprotein component (g2) of Rous sarcoma virus, its amino acid composition, and the nature of its carbohydrate groups.
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KRANTZ, M., LEE, Y. & HUNG, P. Carbohydrate groups in the major glycoprotein of Rous sarcoma virus. Nature 248, 684–686 (1974). https://doi.org/10.1038/248684a0
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DOI: https://doi.org/10.1038/248684a0
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