Abstract
Two closely related polypeptides termed thymin I and II were isolated from bovine thymus by their effect in causing a delayed impairment of neuromuscular transmission in vivo. Purified thymin also induced bone marrow cells to develop the characteristics of intrathymic lymphocytes and it is probable that thymin is a lymphopoietic differentiating hormone of the thymus with secondary neuromuscular effects.
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GOLDSTEIN, G. Isolation of Bovine Thymin: a Polypeptide Hormone of the Thymus. Nature 247, 11–14 (1974). https://doi.org/10.1038/247011a0
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DOI: https://doi.org/10.1038/247011a0
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