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Assessment of cellular origin and EBV status in a PTLD after double cord blood transplantation

Leukemia volume 21, pages 2552–2554 (2007)Cite this article

Epstein–Barr virus-associated post-transplantation lymphoproliferative disorder (EBV-PTLD) has been well described as a complication following allogeneic stem cell transplantation (SCT), but has only recently been reported after cord blood transplantation (CBT).1, 2

Some of the known risk factors for PTLD in bone marrow transplantation are invariably present in CBT and can become contributing factors for PTLD: a relatively low dose of donor T cells, frequent donor–recipient human leukocyte antigen (HLA) disparity and use of antithymocyte globulin (ATG) during conditioning.

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Authors and Affiliations

  1. Istituto di Ematologia, Università Cattolica, Rome, Italy

    G Reddiconto, P Chiusolo, A Fiorini, G Farina, L Laurenti, G Leone & S Sica

  2. Istituto di Anatomia Patologica, Università Cattolica, Rome, Italy

    M Martini

  3. Istituto di Microbiologia, Università Cattolica, Rome, Italy

    S Marchetti & G Fadda

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  1. G Reddiconto
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  2. P Chiusolo
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Correspondence to G Reddiconto.

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Reddiconto, G., Chiusolo, P., Fiorini, A. et al. Assessment of cellular origin and EBV status in a PTLD after double cord blood transplantation. Leukemia 21, 2552–2554 (2007). https://doi.org/10.1038/sj.leu.2404818

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