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Predicting survival for myeloid leukemia after HLA-identical sibling donor allogeneic stem cell transplantation

Leukemia volume 18, pages 1031–1034 (2004)Cite this article

An Erratum to this article was published on 24 May 2004

TO THE EDITOR

Several variables have been previously identified as adverse risk factors for survival after HLA-identical sibling donor allogeneic stem cell transplantation (SCT). Indeed, advanced phase of disease is associated with increased relapse rate and death due to leukemia progression. On the other hand, factors influencing the incidence and severity of graft-versus-host disease (GvHD), such as sex mismatch (female donor and male recipient), older recipient age or positive CMV serology, are related to an increased transplant-related mortality.1,2 However, it is sometimes difficult to know the real impact of these risk factors on transplant outcome when considering a single patient, because favorable and adverse conditions may be present at the same time. In this work, we present a clinical score for predicting the survival of allogeneic SCT from HLA-identical sibling donors for myeloid malignancies on the basis of the evaluation and grading of risk factors available pretransplant.

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Acknowledgements

This study has been financed in part by Grant FIS PI020148 from the Fondo de Investigaciones Sanitarias, Instituto de Salud Carlos III. Ministerio de Sanidad y Consumo.

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Authors and Affiliations

  1. Spanish Group of Hemopoietic Transplant (GETH),

    D Gallardo, R De la Cámara, A Torres, S Brunet, A Jiménez, J C Vallejo, G Sanz, D Serrano, E Carreras, C Martín, C Sanz-Rodríguez, J Sierra, I Espigado, D Caballero & J J Berlanga

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  1. D Gallardo
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  2. R De la Cámara
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  3. A Torres
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  4. S Brunet
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  5. A Jiménez
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  6. J C Vallejo
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  7. G Sanz
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  8. D Serrano
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  9. E Carreras
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  10. C Martín
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  11. C Sanz-Rodríguez
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  12. J Sierra
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  13. I Espigado
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  14. D Caballero
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  15. J J Berlanga
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Corresponding author

Correspondence to D Gallardo.

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On behalf of the Spanish Group of Hemopoietic Transplant (GETH).

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Gallardo, D., De la Cámara, R., Torres, A. et al. Predicting survival for myeloid leukemia after HLA-identical sibling donor allogeneic stem cell transplantation. Leukemia 18, 1031–1034 (2004). https://doi.org/10.1038/sj.leu.2403344

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  • DOI: https://doi.org/10.1038/sj.leu.2403344

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