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Prolonged molecular remission after arsenic trioxide and all-trans retinoic acid for acute promyelocytic leukemia relapsed after allogeneic stem cell transplantation

Leukemia volume 17, pages 1916–1917 (2003)Cite this article

TO THE EDITOR

We read with interest the recent correspondence by Tedeschi et al1 describing an arsenic-induced molecular remission in a patient with relapsed promyelocytic leukemia (APML) postallograft.1 In this patient, the duration of complete remission (CR) from initial remission to relapse preallograft was 12 months, from allograft until relapse was 11 months and postarsenic was 14+ months. We describe a patient, now 10.5 years since the initial diagnosis of APML, in ongoing remission for 36 months postarsenic for third relapse after an allograft.

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References

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Authors and Affiliations

  1. Department of Clinical Haematology and Medical Oncology, Bone Marrow Transplant Service, The Royal Melbourne Hospital, Parkville, Victoria, Australia

    A Grigg & J Szer

  2. Department of Haematology, Royal Hobart Hospital, Hobart, Tas, Australia

    R Kimber

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  1. A Grigg
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  2. R Kimber
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  3. J Szer
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Grigg, A., Kimber, R. & Szer, J. Prolonged molecular remission after arsenic trioxide and all-trans retinoic acid for acute promyelocytic leukemia relapsed after allogeneic stem cell transplantation. Leukemia 17, 1916–1917 (2003). https://doi.org/10.1038/sj.leu.2403050

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