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Evidence of Cross-resistance to a Juvenile Hormone Analogue in Some Insecticide-resistant Houseflies

Abstract

THE widespread occurrence of resistance to present-day insecticides among pest species1,2 has prompted intensive research into alternative means of insect control. The discovery that application of the insect juvenile hormone (JH) or its mimics at certain critical stages of the life cycle leads to developmental abnormalities and death3 has raised hopes of the emergence of a “third generation” of pesticide chemicals4. It has been suggested that insects would be unable to develop resistance to their own juvenile hormone3. Arguments have also been advanced that resistance to hormonal insecticides is not unlikely5,6.

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CERF, D., GEORGHIOU, G. Evidence of Cross-resistance to a Juvenile Hormone Analogue in Some Insecticide-resistant Houseflies. Nature 239, 401–402 (1972). https://doi.org/10.1038/239401a0

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