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Increased Incidence of Rous Sarcomas in Response to Excess Vitamin A

Nature volume 234, pages 547–548 (1971)Cite this article

Abstract

VITAMIN A influences cell differentiation and can produce metaplasia of squamous and mucous secreting epithelia1–3. It is also mitogenic4,5 and influences epithelial tumorigenesis6,7. Previous studies6,8 have demonstrated the co-carcinogenic effect of topical vitamin A palmitate during chemical carcino-genesis in the hamster cheek pouch. We wish to report the effect of topical vitamin A palmitate on Rous sarcomas in chickens.

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Authors and Affiliations

  1. Department of Haematology, Hadassah University Hospital and Hebrew University-Hadassah Medical School,

    A. POLLIACK

  2. Departments of Cancer Research and Immunology, Hebrew University—Hadassah Medical School, Jerusalem

    Z. BEN-SASSON

Authors
  1. A. POLLIACK
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  2. Z. BEN-SASSON
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POLLIACK, A., BEN-SASSON, Z. Increased Incidence of Rous Sarcomas in Response to Excess Vitamin A. Nature 234, 547–548 (1971). https://doi.org/10.1038/234547a0

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