Abstract
FELINE sarcoma virus (FSV) induces malignant tumours in cats1–4, dogs1,2,4, rabbits1,4 and monkeys4,5, and transforms cultured cells from several species including man6,7. Spontaneous regression of tumours induced by FSV has been reported3. We describe here a correlation between the presence of humoral antibodies to virus-associated cell membrane antigens and the failure of cats injected with FSV to develop progressive malignant tumours.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Snyder, S. P., and Theilen, G. H., Nature, 221, 1074 (1969).
Gardner, M. B., Rongey, R. W., Arnstein, P., Estes, J., Sarma, P., Huebner, R. J., and Rickard, C. G., Nature, 226, 807 (1970).
Snyder, S. P., Theilen, G. H., and Richards, W. P. C., Cancer Res., 30, 1658 (1970).
Theilen, G. H., Snyder, S. P., Wolfe, L. G., and Landon, J. C., Comparative Leukemia Research (edit. by Dutcher, R. M.), (Karger, New York, in the press).
Deinhardt, F., Wolfe, L. G., Theilen, G. H., and Snyder, S. P., Science, 167, 881 (1970).
Sarma, P. S., Huebner, R. J., Basker, J. F., Vernon, L., and Gilden, R. V., Science, 168, 1098 (1970).
Chang, R. S., Golden, H. D., and Harrold, B., J. Virol., 6, 599 (1970).
Klein, E., and Klein, G., J. Nat. Cancer Inst., 32, 547 (1964).
Theilen, G. H., Kawakami, T. G., Rush, J. D., and Munn, R. J., Nature, 222, 589 (1969).
Rickard, C. G., J. Small Animal Practice, 10, 615 (1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ESSEX, M., KLEIN, G., SNYDER, S. et al. Correlation between Humoral Antibody and Regression of Tumours induced by Feline Sarcoma Virus. Nature 233, 195–196 (1971). https://doi.org/10.1038/233195a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/233195a0
This article is cited by
-
Effects of orally administered interferon-? on the pathogenesis of feline leukaemia virus-induced erythroid aplasia
Comparative Haematology International (1995)
-
A feline large granular lymphoma and its derived cell line
In Vitro Cellular & Developmental Biology (1990)
-
Reactivation of latent feline leukaemia virus infection
Nature (1982)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.