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Binding of Sheep Red Blood Cells to a Large Population of Human Lymphocytes

Nature volume 230, pages 531–532 (1971)Cite this article

Abstract

WHILE investigating the interaction between antigen–antibody–complement complexes and lymphoid cells1, we have noticed that sheep red blood cells (SRBC) adhered to a surprisingly large proportion of human peripheral blood lymphocytes forming clusters (“rosettes”). We have now examined the conditions in which this interaction occurs, and the frequency of rosette forming lymphocytes in the peripheral blood of normal individuals and a few patients with haematological diseases.

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Authors and Affiliations

  1. Department of Microbiology, School of Medicine of the University of São Paulo,

    WALTRAUT H. LAY & NELSON F. MENDES

  2. Department of Pathology, New York University School of Medicine, New York, 10016

    CELSO BIANCO & VICTOR NUSSENZWEIG

Authors
  1. WALTRAUT H. LAY
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  2. NELSON F. MENDES
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  3. CELSO BIANCO
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  4. VICTOR NUSSENZWEIG
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LAY, W., MENDES, N., BIANCO, C. et al. Binding of Sheep Red Blood Cells to a Large Population of Human Lymphocytes. Nature 230, 531–532 (1971). https://doi.org/10.1038/230531a0

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  • DOI: https://doi.org/10.1038/230531a0

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