Abstract
EARLIER investigations on glycoproteins from connective tissue have been mainly concerned with their chemical characteristics1–6, but very little is known about the biological function of this group of glycoproteins. Our previous observations7 demonstrated the presence of a family of glycoproteins in cardiovascular connective tissue which varied from individual to individual and suggested a genetic basis for their differences. We have isolated glycoproteins from aorta, skin and kidney of bovine, ovine, and human twins and analysed by gel electrophoresis to determine whether variations in glycoproteins occurred among identical and nonidentical twin pairs. Because connective tissue glycoproteins also show enzymatic activities like esterase and phosphatase8, zymograms for these two enzymes were also obtained on polyacrylamide gels. The glycoprotein samples were analysed further by immunoelectrophoresis because they are highly antigenic3–7.
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SRINIVASAN, S., RADHAKRISHNAMURTHY, B., PARGAONKAR, P. et al. Glycoproteins from Connective Tissue of Twins. Nature 229, 58–59 (1971). https://doi.org/10.1038/229058a0
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DOI: https://doi.org/10.1038/229058a0
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