Abstract
CONVENTIONAL antibiotic sensitivity tests require many hours for accurate interpretation. We have now discovered a means of detecting the effects of the antibiotic penicillin on viable bacteria within minutes, by observing changes in the differential light scattered from bacterial suspensions. Sensitivity to penicillin in Staphylococcus aureus is detectable in as little as 3 min after the addition of the antibiotic.
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References
Greenwood, D., and O'Grady, F., Science, 163, 1076 (1959).
Wyatt, P. J., Applied Optics, 7, 1879 (1968).
Wyatt, P. J., Nature, 221, 1257 (1969).
Wyatt, P. J., Nature, 226, 277 (1970).
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BERKMAN, R., WYATT, P. & PHILLIPS, D. Rapid Detection of Penicillin Sensitivity in Staphylococcus aureus. Nature 228, 458–460 (1970). https://doi.org/10.1038/228458a0
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DOI: https://doi.org/10.1038/228458a0
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