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Rabbit Antibody Light Chains and Gene Evolution

Nature volume 228, pages 1040–1044 (1970)Cite this article

Abstract

Several amino-acid positions in the light chains of rabbits are different from the same positions in the light chains of man. This observation suggests that rapid gene expansion is a fundamental mechanism in the evolution of the immune system.

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Author information

Authors and Affiliations

  1. California Institute of Technology, Department of Biology, Pasadena, California, 91109

    LEROY HOOD

  2. The Rockefeller University, New York, 10021

    KLAUS EICHMANN, HENRY LACKLAND & RICHARD M. KRAUSE

  3. Beckman Instrument Company, Palo Alto, California

    JACK J. OHMS

Authors
  1. LEROY HOOD
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  2. KLAUS EICHMANN
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  3. HENRY LACKLAND
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  4. RICHARD M. KRAUSE
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  5. JACK J. OHMS
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HOOD, L., EICHMANN, K., LACKLAND, H. et al. Rabbit Antibody Light Chains and Gene Evolution. Nature 228, 1040–1044 (1970). https://doi.org/10.1038/2281040a0

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