Abstract
7, 12-Dimethylbenz(a)anthracene and one of its hydroxymethyl derivatives have been shown to cause a variety of foetal abnormalities, especially when administered on day 13 of pregnancy. It is suggested that derivatives of benz(a)anthracene must have active side chains situated at C-7 and C-12 for embryopathic activity.
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CURRIE, A., BIRD, C., CRAWFORD, A. et al. Embryopathic Effects of 7,12-Dimethylbenz(a)anthracene and its Hydroxymethyl Derivatives in the Sprague–Dawley Rat. Nature 226, 911–914 (1970). https://doi.org/10.1038/226911a0
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DOI: https://doi.org/10.1038/226911a0
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