Abstract
THE distribution of 91Y and 90Y in tissues after intravenous injection of 91Y or of 90Y + 90Sr has been reviewed1,2. This information is not very helpful in understanding the transfer of 90Y from bone into soft tissues because of the overwhelming contribution of the directly injected Y. But if a mixture of 90Sr and 90Y is injected intramuscularly, 90Sr is free to diffuse into the blood stream but the injected 90Y is almost immobilized locally. The 90Sr is largely taken up into the bones and in these circumstances soft tissue content of 90Y may be an index of transport of 90Y formed in bone out of bone and into the blood stream.
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References
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Edington, G. M., Ward, A. H., Judd, J. M., and Mole, R. H., J. Path. Bact., 71, 277 (1956).
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MOLE, R., WARD, A. Yttrium-90 in Gonads of Monkeys containing Strontium-90. Nature 226, 175 (1970). https://doi.org/10.1038/226175a0
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DOI: https://doi.org/10.1038/226175a0
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