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Model System for Study of Artificially Induced Resistance to Malaria

Nature volume 223, pages 507–509 (1969)Cite this article

Abstract

THERE is still a pressing need for a vaccination model against malarial infection1. The laboratory rodent has been vigorously studied for this purpose since the discovery of Plasmodium berghei more than 20 yr ago2. Of recent reports describing various methods for the induction of resistance to malaria3–5, none have reported good success utilizing non-viable blood stage plasmodial material. The rat has been only partially responsive to such material, while the mouse has remained uniformly refractory6.

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Authors and Affiliations

  1. Department of Zoology, University of Illinois, Urbana, Illinois, 61801

    LAWRENCE E. D'ANTONIO, DAN T. SPIRA & PAUL H. SILVERMAN

  2. Hebrew University, Hadassah Medical School, Jerusalem

    DAN T. SPIRA

Authors
  1. LAWRENCE E. D'ANTONIO
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  2. DAN T. SPIRA
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  3. PAUL H. SILVERMAN
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D'ANTONIO, L., SPIRA, D. & SILVERMAN, P. Model System for Study of Artificially Induced Resistance to Malaria. Nature 223, 507–509 (1969). https://doi.org/10.1038/223507a0

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  • DOI: https://doi.org/10.1038/223507a0

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