Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

DNA Strand Breakage in Cells irradiated with X-rays

Abstract

The presence of oxygen during the exposure of mammalian and bacterial cells to X-rays does not affect the efficiency of single strand breakage of DNA, but in bacteria it interferes with strand rejoining processes which occur during irradiation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Alexander, P., Lett, J. T., and Dean, C. J., Prog. Biochem. Pharmacol., 1, 22 (1965).

    Google Scholar 

  2. Lett, J. T., and Alexander, P., Radiat. Res., 15, 159 (1961).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Freifelder, D., Radiat. Res., 29, 329 (1966).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Hagen, U., and Wellstein, H., Strahlentherapie, 128, 565 (1965).

    CAS  PubMed  Google Scholar 

  5. Hagen, U., Biochim. Biophys. Acta, 134, 45 (1967).

    Article  CAS  Google Scholar 

  6. Blok, J., Luthjens, L. H., and Roos, A. L. M., Radiat. Res., 30, 468 (1967).

    Article  ADS  CAS  PubMed  Google Scholar 

  7. McGrath, R. A., and Williams, R. W., Nature, 212, 534 (1966).

    Article  ADS  CAS  PubMed  Google Scholar 

  8. Lett, J. T., Caldwell, I., Dean, C. J., and Alexander, P., Nature, 214, 790 (1967).

    Article  ADS  CAS  PubMed  Google Scholar 

  9. Freifelder, D., J. Mol. Biol., 35, 303 (1968).

    Article  CAS  PubMed  Google Scholar 

  10. Dean, C. J., Feldschreiber, P., and Lett, J. T., Nature, 209, 49 (1966).

    Article  ADS  CAS  PubMed  Google Scholar 

  11. Charlesby, A., Proc. Roy. Soc., A, 224, 120 (1954).

    Article  ADS  CAS  Google Scholar 

  12. Gupta, N. K., Ohtsuka, E., Weber, H., Chang, S. H., and Khorana, H. G., Proc. US Nat. Acad. Sci., 60, 285 (1968).

    Article  ADS  CAS  Google Scholar 

  13. Gellert, M., Proc. US Nat. Acad. Sci., 57, 148 (1967).

    Article  ADS  CAS  Google Scholar 

  14. Weiss, B., and Richardson, C. C., Proc. US Nat. Acad. Sci., 57, 1021 (1967).

    Article  ADS  CAS  Google Scholar 

  15. Olivera, B. M., and Lehman, I. R., Proc. US Nat. Acad. Sci., 57, 1426 (1967).

    Article  ADS  CAS  Google Scholar 

  16. Gefter, M. L., Becker, A., and Hurwitz, J., Proc. US Nat. Acad. Sci., 58, 240 (1967).

    Article  ADS  CAS  Google Scholar 

  17. Collyns, B., Okada, S., Scholes, G., Weiss, J. J., and Wheeler, C. M., Radiat. Res., 25, 526 (1963).

    Article  ADS  Google Scholar 

  18. Boyce, R. P., and Tepper, M., Virology, 34, 344 (1968).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

DEAN, C., ORMEROD, M., SERIANNI, R. et al. DNA Strand Breakage in Cells irradiated with X-rays. Nature 222, 1042–1044 (1969). https://doi.org/10.1038/2221042a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2221042a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing