Abstract
THE equivalent biological half-time (T½) is defined as This concept was first applied to the interpretation of 137Cs metabolism by Miller1. If retention can be described by a single exponential, the T½ of the exponential equals the equivalent T½. If the retention function is a sum of exponentials (as is the retention of caesium in mammals2,3) the equivalent T½ in equilibrium conditions of constant daily intake or following a single intake is the weighted average of the component half-times4.
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References
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LLOYD, R., ZUNDEL, W., MAYS, C. et al. Short Caesium Half-times in Patients with Muscular Dystrophy. Nature 220, 1029–1031 (1968). https://doi.org/10.1038/2201029a0
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DOI: https://doi.org/10.1038/2201029a0
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