Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Japanese Haemoglobin Variant

Abstract

RECENT haemoglobin surveys in the south-western area of Japan have revealed a great variety of abnormal haemoglobins in Japanese individuals despite the rarity of haemoglobinopathy. In Japan, at least thirteen abnormal haemoglobins have been identified by elucidation of amino-acid substitution, and similar studies are now in progress on ten other variants.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Shibata, S., and Iuchi, I., Acta Haem. J., 24, 51 (1961).

    Google Scholar 

  2. Smithies, O., Adv. Protein Chem., 14, 65 (1959).

    Article  CAS  PubMed  Google Scholar 

  3. Singer, K., Chernoff, A. I., and Singer, L., Blood, 6, 413 (1951).

    CAS  PubMed  Google Scholar 

  4. Goldberg, C. A. J., Clin. Chem., 4, 146 (1958).

    CAS  Google Scholar 

  5. Ueda, S., Jap. J. Clin. Hemat., 3, 26 (1958).

    Google Scholar 

  6. Shibata, S., Iuchi, I., Ueda, S., Miyaji, T., and Takeda, I., Acta Haem. Jap., 25, 675 (1962).

    CAS  Google Scholar 

  7. Take, T., J. Biochem., 49, 206 (1961).

    Article  CAS  PubMed  Google Scholar 

  8. Anson, M. L., and Mirsky, A. E., J. Gen. Physiol., 13, 469 (1930).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Clegg, J. S., Naughton, M. A., and Weatherall, D. J., J. Mol. Biol., 19, 91 (1966).

    Article  CAS  PubMed  Google Scholar 

  10. Jones, R. T., Cold Spr. Harb. Symp. Quant. Biol., 24, 297 (1964).

    Article  Google Scholar 

  11. Ingram, V. M., Biochim. Biophys. Acta, 28, 539 (1958).

    Article  CAS  PubMed  Google Scholar 

  12. Baglioni, C., Biochim. Biophys. Acta, 48, 392 (1961).

    Article  CAS  PubMed  Google Scholar 

  13. Piez, K. A., and Morris, L., Anal. Biochem., 1, 187 (1960).

    Article  CAS  PubMed  Google Scholar 

  14. Braunitzer, G., Hilse, K., Rudloff, V., and Hilschmann, N., Adv. Protein Chem., 19, 1 (1964).

    Article  CAS  PubMed  Google Scholar 

  15. Gerald, P. S., and Eflon, M. L., Proc. US Nat. Acad. Sci., 47, 1758 (1961).

    Article  ADS  CAS  Google Scholar 

  16. Ranney, H. M., Jacobs, A. S., and Nagel, R. L., Nature, 213, 876 (1967).

    Article  ADS  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MIYAJI, T., OHBA, Y., YAMAMOTO, K. et al. Japanese Haemoglobin Variant. Nature 217, 89–90 (1968). https://doi.org/10.1038/217089a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/217089a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing