Abstract
WHEN the serum from patients with Burkitt-type lymphoma is incubated with living suspensions consisting mostly of Burkitt tumour cells, the cell surfaces become coated with immunoglobulin as detected by the fluorescent antibody technique1. Evidence suggests that this surface reaction is correlated with the occurrence of a virus like particle, and that this particle is also associated with a cytoplasmic antigen detected by the fluorescent antibody technique2, but there are good reasons to distinguish between this and the membrane fluorescence phenomenon demonstrable on the living cell.
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References
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Smith, R. T., Klein, G., Klein, E., and Clifford, P., Progress in Transplantation (in the press, 1967).
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SMITH, R., KLEIN, G., KLEIN, E. et al. Mixed Agglutination between Established Burkitt Cell Lines and Fresh Biopsy Specimens. Nature 216, 693–694 (1967). https://doi.org/10.1038/216693a0
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DOI: https://doi.org/10.1038/216693a0
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