Abstract
A NUMBER of neutral glycolipids which contain ceramide have been isolated from a variety of mammalian tissues including brain1, liver2,3, serum2, spleen2,4, erythrocyte2,3,5–7, kidney8–12, lung13 and ascites tumours14,15. The composition of glycolipids in strain-specific ascites tumours differed in different strains of mice15, which suggested that the composition of tumour glycolipids could reflect the specificity of either the tumour or the mouse strain. Further studies showed that there were significant differences in the glycolipid compositions of the kidneys between certain strains of normal mice. We have now compared the glycolipids of the kidneys of C3H mice carrying a BP8 ascites tumour with those of the kidneys of normal C3H mice and with those of the BP8 tumour and the results with reference to the tumour-carrying mice are of considerable interest and are the subject of this communication.
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ADAMS, E., GRAY, G. Effect of BP8 Ascites (Sarcoma) Tumours on Glycolipid Composition in Kidneys of Mice. Nature 216, 277–278 (1967). https://doi.org/10.1038/216277a0
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DOI: https://doi.org/10.1038/216277a0
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