Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Site of Attachment of Retinal in Rhodopsin

Nature volume 216, pages 1178–1181 (1967)Cite this article

An Erratum to this article was published on 06 January 1968

Abstract

On illumination, rhodopsin passes through several unstable intermediates to a final mixture of retinal and opsin. One of these intermediates, metarhodopsin II, can be reduced by sodium borohydride to bind irreversibly the prosthetic group retinal to opsin in secondary amino linkage.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hubbard, R., Bownds, D., and Yoshizawa, T., Cold Spring Harbor Symp. Quant. Biol., 30, 301 (1965).

    Article  CAS  Google Scholar 

  2. Collins, F. D., Nature, 171, 469 (1953).

    Article  CAS  ADS  Google Scholar 

  3. Morton, R. A., and Pitt, G. A. J., Biochem. J., 59, 128 (1955).

    Article  CAS  Google Scholar 

  4. Bownds, D., and Wald, G., Nature, 205, 254 (1965).

    Article  CAS  ADS  Google Scholar 

  5. Matthews, R. G., Hubbard, R., Brown, P. K., and Wald, G., J. Gen. Physiol., 47, 215 (1963).

    Article  CAS  Google Scholar 

  6. Hubbard, R., Proc. Nat. Phys. Lab. Symp. No. 8, Paper 4 (HMSO, London 1958).

  7. Hubbard, R., J. Gen. Physiol., 37, 381 (1954).

    Article  CAS  Google Scholar 

  8. Bownds, D., thesis, Harvard Univ. (1967).

  9. Bownds, D., Fed. Proc., 25, Pt. 1, 787 (1966).

    Google Scholar 

  10. Akhtar, M., Blosse, P. T., and Dewhurst, P. B., Chem. Commun., 631 (1967).

  11. Albrecht, G., J. Biol. Chem., 229, 477 (1957).

    CAS  PubMed  Google Scholar 

  12. Bownds, D., Fed. Proc., 26, 601 (1967).

    Google Scholar 

  13. Brown, P. K., and Wald, G., J. Biol. Chem., 222, 865 (1956).

    CAS  PubMed  Google Scholar 

  14. Pitt, G. A. J., Collins, F. D., Morton, R. A., and Stok, P., Biochem. J., 59, 122 (1955).

    CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Author notes

  1. DERIC BOWNDS

    Present address: Department of Neurobiology, Harvard Medical School, Boston, Massachusetts

Authors and Affiliations

  1. Biological Laboratories of Harvard University, Cambridge, Massachusetts

    DERIC BOWNDS

Authors
  1. DERIC BOWNDS
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

BOWNDS, D. Site of Attachment of Retinal in Rhodopsin. Nature 216, 1178–1181 (1967). https://doi.org/10.1038/2161178a0

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2161178a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing