Abstract
Burka and DeBellis1 have compared the disappearance of ribosomes and polyribosomes during in vivo erythroid maturation in the rabbit. In order to study in vivo maturation of circulating erythroid cells labelled with isotope, unobscured by the continued release of new cells from the marrow, they injected labelled cells from a donor animal into a lethally irradiated recipient which continued to receive colchicine. In contrast to previous work2 which they cite on this subject, they failed to find a disproportionate loss of polyribosomes and an increasing proportion of single ribosomes during maturation.
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References
Burka, E. R., and DeBellis, R., Nature, 213, 724 (1967).
Rowley, P. T., Nature, 208, 244 (1965).
Warner, J. R., Knopf, P. M., and Rich, A., Nature, 49, 122 (1963).
Eikenberry, E. F., and Rich, A., Proc. US Nat. Acad. Sci., 53, 668 (1965).
Warner, J. R., Rich, A., and Hall, C. E., Science, 138, 1399 (1962).
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ROWLEY, P. Disappearance of Ribosomes and Polyribosomes during in vivo Erythroid Maturation. Nature 216, 1109–1110 (1967). https://doi.org/10.1038/2161109a0
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DOI: https://doi.org/10.1038/2161109a0
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