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Enzyme Mechanism of Aminoacetone Metabolism by Micro-organisms

Nature volume 215, pages 887–888 (1967)Cite this article

Abstract

ALTHOUGH aminoacetone was first recognized as a microbial metabolite in 1958 (ref. 1), and found to be formed from L-threonine1–5, glycine plus a source of acetyl-CoA1,2,4,5, or isopropanolamine5,6 (1-aminopropan-2-ol) by a variety of micro-organisms, it has only recently been found that the amino ketone is further metabolized by resting cell suspensions of some bacteria7. The rapid utilization of aminoacetone by extracts free from cells has now been demonstrated and information of the enzyme mechanism of aminoacetone metabolism is available.

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Authors and Affiliations

  1. Department of Biochemistry, Johnston Laboratories, University of Liverpool,

    I. J. HIGGINS, J. M. TURNER & A. J. WILLETTS

Authors
  1. I. J. HIGGINS
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  2. J. M. TURNER
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  3. A. J. WILLETTS
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HIGGINS, I., TURNER, J. & WILLETTS, A. Enzyme Mechanism of Aminoacetone Metabolism by Micro-organisms. Nature 215, 887–888 (1967). https://doi.org/10.1038/215887a0

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