Abstract
NOTABLE improvements in immunohistological techniques and the availability of a new fauna prompted us to apply anti-kidney sera previously described1 to further studies of the species distribution of kidney-specific antigens. We used two sera prepared by immunizing rabbits with microsomal material from human and hamster kidneys respectively, and examined their cross-reactivity with the kidneys of other species by immunofluorescence2. Contrary to the earlier reports that cross-reactions are limited to mammals, birds and fish, we found that both sera cross-reacted with all kidneys examined from vertebrates of every class. There was also some cross-reaction with seminal vesicle epithelium in the few species studied.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Nairn, R. C., Ghose, T., Fothergill, J. E., and McEntegart, M. G., Nature, 196, 385 (1962).
Nairn, R. C., Fluorescent Protein Tracing, second ed. (Livingstone, Edin-burgh, 1964).
Nairn, R. C., Ghose, T., and Tannenberg, A. E. G., Brit. J. Cancer, 20, 756 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
NAIRN, R., GHOSE, T. & MAXWELL, A. Distribution of Nephric Antigens in Australian Vertebrates. Nature 215, 867–868 (1967). https://doi.org/10.1038/215867a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/215867a0
This article is cited by
-
Renal tubular antigen excretion in normal human urine. I. Immunochemical identification
Kidney International (1973)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.