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Crystalline Aflatoxin M1 from Urine and Milk

Abstract

Allcroft and Carnaghan1 and de Iongh et al.2 reported the appearance in milk of a compound related to aflatoxin B1, and Allcroft et al.3 showed by thin-layer chromatography and ultra-violet studies that a similar factor appeared in the urine of sheep given mixed aflatoxins. Holzapfel et al.4 isolated the urinary compound and established that it was aflatoxin M1 (Fig. 1).

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References

  1. Allcroft, R., and Carnaghan, R. B. A., Vet. Rec., 75, 259 (1963).

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  2. de Iongh, H., Vles, R. O., and van Pelt, J. G., Nature, 202, 466 (1964).

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  3. Allcroft, R., Rogers, H., Lewis, G., Nabney, J., and Best, P. E., Nature, 209, 154 (1966).

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  4. Holzapfel, C. W., Steyn, P. S., and Purchase, I. F. H., Tetrahedron Lett., 25, 2799 (1966).

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MASRI, M., LUNDIN, R., PAGE, J. et al. Crystalline Aflatoxin M1 from Urine and Milk. Nature 215, 753–755 (1967). https://doi.org/10.1038/215753a0

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