Abstract
Allcroft and Carnaghan1 and de Iongh et al.2 reported the appearance in milk of a compound related to aflatoxin B1, and Allcroft et al.3 showed by thin-layer chromatography and ultra-violet studies that a similar factor appeared in the urine of sheep given mixed aflatoxins. Holzapfel et al.4 isolated the urinary compound and established that it was aflatoxin M1 (Fig. 1).
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References
Allcroft, R., and Carnaghan, R. B. A., Vet. Rec., 75, 259 (1963).
de Iongh, H., Vles, R. O., and van Pelt, J. G., Nature, 202, 466 (1964).
Allcroft, R., Rogers, H., Lewis, G., Nabney, J., and Best, P. E., Nature, 209, 154 (1966).
Holzapfel, C. W., Steyn, P. S., and Purchase, I. F. H., Tetrahedron Lett., 25, 2799 (1966).
Shotwell, O. L., Hesseltine, C. W., Stubblefield, R. D., and Sorenson, W. G., App. Microbiol., 14, 425 (1966).
Keppler, J. G., and de Iongh, H., Fd. Cosmet. Toxicol., 2, 675 (1964).
Andrellos, P. J., and Reid, G. R., J.A.O.A.C., 47, 801 (1964).
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MASRI, M., LUNDIN, R., PAGE, J. et al. Crystalline Aflatoxin M1 from Urine and Milk. Nature 215, 753–755 (1967). https://doi.org/10.1038/215753a0
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DOI: https://doi.org/10.1038/215753a0
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