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Induction of Tumours in Hamsters with Infectious Canine Hepatitis Virus

Abstract

A NUMBER of adenoviruses which infect human beings and avian and other animal species have been shown to induce tumours in newborn golden Syrian hamsters. Included among these are several human adenoviruses1–7, chicken embryo lethal orphan (CELO) virus8, a number of simian adenoviruses9, and bovine adenovirus type 3 (ref. 10). We report here the induction of tumours in newborn hamsters by a canine adenovirus, the causative agent of infectious canine hepatitis (ICH). The tumour cells were shown to contain complement-fixing antigens for ICH virus.

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SARMA, P., VASS, W., HUEBNER, R. et al. Induction of Tumours in Hamsters with Infectious Canine Hepatitis Virus. Nature 215, 293–294 (1967). https://doi.org/10.1038/215293a0

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